Those are Saddlemen Rigid Mount Cruisn' bags, Large.
The throttle side grip is easy, just unscrew the switch assembly and use needlenose to disconnect the cables. Remove end weight (they screw in) then reverse the process with the new grip.
The clutch isde is more complicated and I nearly screwed it up. You remove the end weight, and run a flathead between the grip and bar, or shoot compressed air to release it from the glue that bonds it to the bar. Get the old glue off the bar, seriously get it all! That nearly ruined the rubber on the new grip by me going "good enough". You then test fit the grip so you can get an idea of the alignment of the rubber and your hand. Now remove it, put some of the supplied glue on the bar, not too much, I'd suggest spots around the bar, then QUICKLY twist the grip on while lightly tapping the end with a rubber mallet. Get it rotated to the fit you want and by then it's bonded.
On one of my old bikes I actually reused the end weights with my ISO grips and it looked great, and less vibration. I might look into black chroming my end weights and try it out.